The investigational oral drug inhibits the so-called Heat Shock Factor-1 (HSF1) pathway, and was discovered by scientists at the Cancer Research UK Cancer Therapeutics Unit at The Institute of Cancer ...

IL-21-engineered NK cells offer superior safety and long-term control for glioblastoma, Merck halted 2 phase 3 KEYNOTE trials of pembrolizumab, and the MonumenTAL-1 trial data is discussed.

RPE-1 cells adapt to aneuploidy in vitro, a process characterized by reduced CIN and inflammation. This study shows that this ...

Approximately 66% of funding of HSF1-3 (around £800 million) was spent on households with children. "Additionally, DWP is ...

THOUSANDS of families struggling with financial hardships can now claim cost of living payments worth up to £500. Cash-strapped households can get access to the money through the ...

Check out our latest reviews. Scroll down and you'll see that the content is split into our various categories. We have listed the latest ten reviews for each, but you can drill down further by ...

CaMKII activates the HRI/eIF2α signaling pathway and inhibits the proteotoxicity induced by proteasome inhibition through ...

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The drug, called NXP800, was discovered at The Institute of Cancer Research, London, and targets the pathway regulated by the HSF1 transcription factor. HSFI is a ‘master switch’ in cells that ...