研究人员进一步探究PCr对GSCs维持和GBM进程的潜在影响。生物发光成像结果显示，在原位GBM异种移植小鼠模型中，CKB基因的缺失，降低了PCr水平，抑制了GSCs的增殖和GBM生长，并且有效延长了小鼠生存期（图2A-B）。使用 ...

胶质母细胞瘤（GBM）被归类为四级胶质瘤，是中枢神经系统常见的内源性恶性肿瘤。尽管实施了包括较大限度手术切除、放疗和以替莫唑胺（TMZ）为基础的化疗联合后续序贯TMZ治疗的标准治疗方案，但新诊断的GBM患者的平均总生存（OS）时间仅为14.6个月。胶质母细胞瘤干细胞（GSCs）是一小部分具有自我更新和多向分化能力的GBM细胞，被认为是GBM肿瘤发生和发展的责任方。GSCs还具有辐射抵抗、化疗抵抗、 ...

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NC RaineLocal Journalism Initiative ReporterEagle Feather NewsSt. Frances Cree Bilingual School in Saskatoon, the largest ...

Francine is now a hurricane as it heads closer and closer to the Louisiana shoreline. Mobile is expected to see impacts such as rain, rough surf, storm surge/coastal ...

Sharefest and Marathon petroleum team up to beautify Dominguez Elementary Sharefest believes in the power of collaboration, and we're excited to share the success of our latest project with Marathon ...