The antipsychotic drug haloperidol is often used in emergency care to treat psychoses induced by methamphetamine, but a recently published animal study by Hatzipetros et al. warns that this ...

His lab first discovered that excitotoxicity might be a common pathophysiological process in sporadic ALS, which led to the use of the drug riluzole as a treatment for ALS. Rothstein made discoveries ...

and excitotoxicity. More than 40 studies have used progesterone for treatment after traumatic brain injury in adult animal models, with results summarized in tabular form. However, very few ...

Cardiovascular physiology, neurophysiology and exercise science. Neural mechanisms of cardiovascular diseases and metabolic disorders. Neural mechanisms of exercise training in regulating autonomic ...

Thus, these transporters have an essential role of maintaining extracellular glutamate concentrations below neurotoxic levels. Pathologically high levels of extracellular glutamate can cause ...

In recent years, peptides have emerged as critical players in various fields of biological and molecular research. Among ...

The researchers for the new study also noted that riboflavin is known to improve "oxidative stress, mitochondrial dysfunction, neuroinflammation, and glutamate excitotoxicity," all of which are ...

PROG and its metabolites can upregulate gene activity through their direct actions on the PROG intranuclear receptor, but they can also act at the NMDA receptor to reduce excitotoxicity and at the ...