it coordinates potentially dangerous steps in the base excision repair pathway. Figure 1: Schematic representation of single-nucleotide BER and alternatives for aborted intermediates. Recent ...

The researchers identified at least three distinct mechanisms that address formaldehyde-induced DNA damage: 1) in the ...

AMeD syndrome is a severe genetic condition found in children that presents with accelerated aging, global developmental ...

A work co-led by researchers of the Josep Carreras Leukaemia Research Institute and of the University of Cologne uncovered ...

Repair reactions involve the excision of chemically altered or mispaired bases from the DNA duplex. Resulting gaps are filled in by DNA polymerases; this reaction leaves a nick at or flanking the site ...

Researchers have uncovered the mechanisms that protect the genome from the metabolic toxin formaldehyde in AMeD, a rare congenital disorder of premature aging and myeloid leukemia development. The ...

AMeD syndrome is a severe genetic condition found in children that present with accelerated aging, global developmental delay and bone marrow failure, among others, progressing to Myelodysplastic ...

Mol Biol Cell, 31: 348-359. Feng J, Yao S, Dong Y, Hu J, Whiteway M, Feng J. Nucleotide excision repair protein Rad23 regulates cell virulence independent of Rad4 in Candida albicans (2020) mSphere ...

Excision introduced Subsidia in an animated video he played on Friday, Sept. 25 before his live stream set for Couch Lands—the virtual rendition of his Lost Lands music festival. This marked his ...