Pacritinib,商品名为Vonjo,是一种用于治疗骨髓纤维化的抗癌药物。它是一种大环蛋白激酶抑制剂。它主要抑制Janus 激酶 2 (JAK2) 和Fms 样酪氨酸激酶 3\CD135 (FLT3)。
2023年10月26日,首个完整的HIV-1长效注射治疗方案:万凯锐 (卡替拉韦)和瑞卡必 (利匹韦林),获中国国家药品监督管理局 (NMPA) 批准。该方案每两个月注射一次,不用与口服 ...
Most drugs are metabolized by CYP3A enzymes, and variations in expression levels of these enzymes are believed to determine whether patients will have a positive or adverse drug response.
决奈达隆的商品名为Multaq ,是赛诺菲安万特公司开发的III 类抗心律失常药物。该药物于 2009 年 7 月获美国食品药品管理局 (FDA)批准。除了用于治疗心律失常外,它还被推荐作为胺碘酮的替代品,用于治疗心房颤动和心房扑动,适用于心脏已恢复正常节律或接受药物治疗或电击治疗,即直流电复律 (DCCV) 以维持正常节律的患者。
Your body clears Xanax through a pathway known as cytochrome P450 3A (CYP3A). Medications that inhibit CYP3A4 make it harder for your body to break down Xanax, which increases your risk of overdosing.
Because CYP isoenzymes metabolize a large number of structurally diverse drugs and chemicals, most of the variant genotypes of the CYP2D6, CYP2C9, CYP2C19, and CYP3A families have been identified ...
CYP3A Inhibitors: When BRUKINSA is co-administered with a strong CYP3A inhibitor, reduce BRUKINSA dose to 80 mg once daily. For coadministration with a moderate CYP3A inhibitor, reduce BRUKINSA ...
Tabs: Avoid concomitant strong CYP3A inhibitors or P-gp inhibitors. Concomitant with moderate CYP3A inhibitors or P-gp inhibitors; monitor. Concomitant with sensitive CYP3A substrates (eg ...
Detailed price information for Agios Pharmaceuticals (AGIO-Q) from The Globe and Mail including charting and trades.
Alprazolam 0.25mg, 0.5mg. 1mg, 2mg; scored tabs; orange flavor. ≥18yrs: Anxiety: Initially 0.25–0.5mg three times daily. May increase at 3–4 day intervals to 4mg/day in divided doses.
FILSPARI® (sparsentan) received full FDA approval as the only non-immunosuppressive treatment that significantly slows kidney function decline in ...