Pacritinib，商品名为Vonjo，是一种用于治疗骨髓纤维化的抗癌药物。它是一种大环蛋白激酶抑制剂。它主要抑制Janus 激酶 2 (JAK2) 和Fms 样酪氨酸激酶 3\CD135 (FLT3)。

药品分类：抗肿瘤药物非小细胞肺癌（NSCLC）是全球范围内常见且治疗难度较大的一种癌症类型。针对这种疾病的治疗，科学家们一直在寻求更有效的治疗方案。氟泽雷塞片（商品名：达伯特），一种革命性的口服靶向药物，专门针对KRAS ...

The FDA informed Intercept that it is unable to approve the sNDA in its current form, consistent with the outcome of the Gastrointestinal Drugs Advisory Committee (GIDAC) meeting in September 2024. In ...

After a person quits smoking, an important consideration is how quickly the induction of CYP1A2 dissipates. The primary pharmacokinetic interactions with smoking occur with drugs that are CYP1A2 ...

The levels of caffeine in your blood could affect the amount of body fat you carry, a factor that in turn could determine ...

Figure 1 lists the pharmacokinetic drug interactions with smoking. The most clinically significant interactions appear in the shaded rows and are discussed below.

2. 罗红霉素：属大环内酯类抗菌药物，可抑制CYP3A4和CYP1A2的活性。当罗红霉素与氨茶碱合用时，罗红霉素可抑制氨茶碱的代谢，升高氨茶碱血药浓度 ...

Dr Grimaldi says if you carry the genetic variation CYP1A2 (AA), for example, you will “almost certainly” metabolise caffeine faster than someone who doesn’t, and therefore feel its effects ...

Best caffeine pills in 2024 to keep you going - The energising tablets offer an easy, convenient and quick alternative to a ...

Famotidine 20mg/50mL; soln for IV infusion; preservative-free. Famotidine is a competitive inhibitor of histamine-2 (H2) receptors. The primary clinically important pharmacologic activity of ...