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What the researchers found was compelling: notochord cells secrete connective tissue growth factor (CTGF)--a recently characterized protein with multifunctional anabolic properties. CTGF gene ...

Connective tissue diseases are a heterogeneous group of autoimmune disorders that affect any of the body's connective tissues. These disorders can be inherited or acquired, and can present with a ...

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They were the last throw of the dice for pamrevlumab, which has been vying to become the first therapy targeting connective tissue growth factor (CTGF) to come to market. The drug was earlier ...

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Tissues are ensembles of similar or compatible types of animal or plant cells that together carry out a specific function. In the human body there are four categories of tissues: epithelial ...

Gene therapy-mediated silencing of connective tissue growth factor (CTGF) and overexpression of mitochondrial superoxide dismutase (Mn-SOD) has been shown to reduce radiation-induced damage in a rat ...

It focuses on the hypoxia-inducible factor and connective tissue growth factor biology to develop medicines for the treatment of anemia, fibrotic disease, and cancer. The company was founded by ...