The matchup: Two doses of psilocybin, the active ingredient in “magic mushrooms,” against a six-week course of the popular antidepressant escitalopram, often sold as Lexapro or Cipralex.

Share on Pinterest A new clinical trial looks at how psilocybin compares to a commonly prescribed antidepressant. Image credit: The Washington Post/Getty Images. About 5% of adults worldwide live ...

But while SSRI antidepressants can help in offering relief from symptoms, in comparison, psilocybin, or magic mushrooms, might be more effective, according to a recent study. “This is important ...

But what is really needed is a comparison of the long-term effect of psilocybin with another treatment (an antidepressant) or a placebo. Ideally, neither participants nor staff should be aware of ...

Not enough to draw conclusions It would be tempting to conclude from this study that psilocybin works just as well as ...

Psilocybin, the best-known psychedelic substance derived from "magic" mushrooms, is a Schedule I substance: an illegal drug considered to have no medical use and high potential for abuse.

Massachusetts voters have a far-out opportunity on Election Day: They can make certain psychedelic drugs legal in the Bay State. If Question 4 passes on Nov. 5, Massachusetts would permit adults ...