CDKN2

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1.

Results : The deletion rate of the CDKN2 gene was 60%in gliomas and was significantly higher in high grade gliomas than in low grade gliomas.

结果：胶质瘤 CDKN2 基因丢失率为 60%，且高级别胶质瘤基因丢失率显著高于低级别肿瘤；

2.

The CDKN2 gene deletions were also detected in meningiomas, neurinomas, pituitary adenomas and metastatic carcinomas to a different degree .

脑膜瘤、神经鞘瘤、垂体腺瘤及转移瘤亦存在不同程度 CDKN2 基因的丢失。

3.

Conclusion : CDKN2 gene loss might bear some relations to the tumor occurrence and transformation in central nervous system .

结论：CDKN2 基因的丢失与中枢神经系统肿瘤的发生、发展有一定的关系。

4.

To evaluate the occurrence of CDKN2 gene alteration, ons in tumors of central nervous system .

目的：探讨中枢神经系统肿瘤 CDKN2 基因的丢失情况。