Glycosylation - Wikipedia
网页Glycosylation is the process by which a carbohydrate is covalently attached to a target macromolecule, typically proteins and lipids. This modification serves various functions. [5] For instance, some proteins do not fold correctly unless they are glycosylated. [2]
Global view of human protein glycosylation pathways and functions - Nature
网页2020年10月21日 · Most proteins are glycosylated through 1 or more of 14 distinct glycosylation pathways that in humans involve at least 173 glycosyltransferases as well as many other enzymes that modify glycans.
Glycosylation: mechanisms, biological functions and clinical ...
网页2024年8月5日 · The glycosylation pathway produces different protein forms of modified proteins that play a role in many biological functions.
A1C test - Mayo Clinic
网页2022年12月1日 · The A1C test is a common blood test used to diagnose type 1 and type 2 diabetes. If you're living with diabetes, the test is also used to monitor how well you're managing blood sugar levels. The A1C test is also called the glycated hemoglobin, glycosylated hemoglobin, hemoglobin A1C or HbA1c test.
Glycosylation in health and disease - Nature Reviews Nephrology
网页2019年3月11日 · Glycosylation refers to the addition of carbohydrate chains to proteins and lipids. In this Review, the authors discuss the broad role of glycans in immunity, cancer, xenotransplantation and ...
An Overview of Glycosylation and its Impact on Cardiovascular …
网页2021年11月16日 · Glycosylation is the most frequent post-translational modification in proteins because about half of the known proteins in eukaryote cells are glycosylated.
Cellular Organization of Glycosylation - Essentials of Glycobiology ...
网页Cell-surface membrane proteins like receptors, adhesion molecules, and channels are typically glycosylated, and this modification can promote their proper folding, ensure their stability, and impact function.
Glycosylation in health and disease - PMC - National Center for ...
网页In fact, changes in glycosylation can modulate inflammatory responses, enable viral immune escape, promote cancer cell metastasis or regulate apoptosis; the com position of the glycom e also affects kidney function in health and disease.
Protein glycosylation: Current Biology - Cell Press
网页2019年4月1日 · What is protein glycosylation? Protein glycosylation is the covalent attachment of single sugars or glycans, i.e., multi-sugar polysaccharides or complex oligosaccharides, to select residues of target proteins.
Glycosylation in Cellular Mechanisms of Health and Disease
网页2006年9月8日 · Glycosylation produces different types of glycans (or glycoconjugates) that are typically attached to cellular proteins and lipids (Figure 1). Protein glycosylation encompasses N-glycans, O-glycans, and glycosaminoglycans …