Vitamin B12 - Wikipedia
网页Vitamin B 12 is derived from a tetrapyrrolic structural framework created by the enzymes deaminase and cosynthetase which transform aminolevulinic acid via porphobilinogen and hydroxymethylbilane to uroporphyrinogen III. The latter is the first macrocyclic intermediate common to heme, chlorophyll, siroheme and B 12 itself.
vitamin B12 | C63H88CoN14O14P | CID 5311498 - PubChem
网页Description. Cyanocobalamin (commonly known as Vitamin B12) is a highly complex, essential vitamin, owing its name to the fact that it contains the mineral, cobalt. This vitamin is produced naturally by bacteria, and is necessary for …
Vitamin B₁₂: Cobalamin - Chemistry LibreTexts
网页2022年7月14日 · The examination of the vitamin’s molecular structure helps scientists to have a better understanding of how the body utilizes Vitamin B 12 into building red blood cells and preventing pernicious anemia syndromes.
Structural detail for Vitamin B12 - Bristol
网页The center-piece in the structure is of course the cobalt(III), the octahedral coordination to five nitrogens and a carbon is common to all three cobalamins, and can be found in a number of simple coordination complexes.
Vitamin B12 | Sources, Deficiency & Health Effects | Britannica
网页2024年9月13日 · The vitamin, which is unique in that it contains a metallic ion, cobalt, has a complex chemical structure as shown: Vitamin B 12 occurs in several forms, called cobalamins; cyanocobalamin is the principal one used in vitamin supplements and pharmaceuticals.
Vitamin B12: Unique Metalorganic Compounds and the Most …
网页2010年4月30日 · The chemistry and biochemistry of the vitamin B 12 compounds (cobalamins, XCbl) are described, with particular emphasis on their structural aspects and their relationships with properties and function.
Vitamin B12 in Foods, Food Supplements, and Medicines—A …
网页2022年12月28日 · Four vitamin B 12 forms—cyanocobalamin, hydroxocobalamin, 5′-deoxyadenosylcobalamin, and methylcobalamin—are currently used for supplementation and, here, we provide an overview of their biochemical role, bioavailability, and efficacy in different dosage forms.
Vitamin B12 - ScienceDirect
网页2020年1月1日 · Structure of vitamin B12. The structure of vitamin B12 (OH-Cbl) is shown in Fig. 15.1. It is a very complex molecule containing a corrin ring, (which coordinates a cobalt molecule), a base (5,6-dimethylbenzimidazole), a sugar, and an aminopropanol group.
Vitamin B12 - SpringerLink
网页Figure 1. Structure of the different vitamin B12 vitamers. Full size image. Only microorganisms are able to synthesize vitamin B12. Microbiological vitamin B12 synthesis in humans takes place, however, in the lower intestine where the body cannot sufficiently absorb the vitamin. Therefore, humans have to supply the vitamin via the diet.
Vitamin B12 transport from food to the body's cells—a ... - Nature
网页2012年5月1日 · A coherent vitamin B 12 (B 12) transport pathway from food to the body's cells has now been delineated; the pathway includes an ABC transporter for cellular B 12 efflux and a receptor for...
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